System-wise Notes,
organized for structured study.
Every major topic, grouped by organ system.
Nine organ-system files organized topic-by-topic for structured USMLE Step 1 study — built to help you work through a system methodically, front to back.
Built for real study sessions
These notes are written for the version of you sitting down to actually learn a system — not the one skimming ten minutes before walking in. They keep growing and getting revised as new material is added.
Nine organ systems, one index
Arranged in the order they're typically taught — from circulation and gas exchange through to the nervous system.
Cardiovascular
Embryology through arrhythmias, ischemia, and heart failure pharmacology.
Open notesRespiratory
Lung volumes, gas exchange, obstructive/restrictive disease, and pulmonary pharm.
Open notesRenal
Nephron physiology, acid-base, electrolyte disorders, and glomerular disease.
Open notesGastrointestinal
GI embryology, motility, malabsorption, hepatobiliary and GI pharmacology.
Open notesHematology & Oncology
Anemias, coagulation disorders, transfusion medicine, and heme malignancies.
Open notesEndocrine
Hormone axes, thyroid and adrenal disease, diabetes, and endocrine pharmacology.
Open notesReproductive
Sexual development, the menstrual cycle, pregnancy, and reproductive pathology.
Open notesMusculoskeletal
Bone and joint disease, peripheral nerve anatomy, muscle physiology, and analgesics.
Open notesNervous System
Neuroanatomy, pathways, cranial nerves, and clinical neuro-pathology.
Open notes